Cupriavidus pauculus (Ralstonia paucula) concomitant meningitis and septicemia in a neonate: First case report from India.

Ralstonia paucula (formerly classifi ed as CDC (Centre for Disease Control) group IVc-2, Wautersia paucula; recently renamed as Cupriavidus pauculus) is an environmental Gram-negative bacillus isolated from water sources and can cause serious human infections. Patients recover bacteriologically indicating low virulence. A total of 32 cases have been reported world-wide, but no isolation has ever been reported from cerebrospinal fl uid or in India. The fi rst case of R. paucula meningitis and septicemia is being reported here along with the brief summary of cases reported world-wide.

Bacteriemia asociada a catéter por Cupriavidus pauculus / Cupriavidus pauculus catheter related bacteremia

Cupriavidus pauculus es un bacilo Gram negativo con metabolismo oxidativo, que se ha aislado de muestras de agua y suelo, pero raramente de personas como entidad clínica. En la literatura científica existen menos de veinte artículos de reportes de caso de este microorganismo. La mayoría han sido pacientes con algún tipo de inmunosupresión, sometidos a procedimientos invasivos, especialmente de tipo vascular, y que han requerido múltiple manejo antibiótico. Cupriavidus pauculus ha mostrado baja virulencia y sensibilidad antibiótica, principalmente a trimetoprim-sulfametoxazol, betalactámicos de amplio espectro y quinolonas. Se presenta el caso de una paciente de 55 años con antecedentes de trasplante renal, que ingresó con infección de tejidos blandos y a quien se le diagnosticó bacteriemia asociada a catéter por C. pauculus durante la hospitalización.

Cupriavidus pauculus it’s a gram-negative bacillus with an oxidative metabolism that has been isolated in water and soil samples, but rarely in people clinical entities. There are less than 20 articles case-reported about this microorganism. Most of which have been patients with some type of immune impairment, mostly subjects with invasive vascular procedures, who had required multiples antibiotic management. Cupriavidus pauculus has mainly shown a low virulence and antibiotic sensibility to trimethoprim-sulfametoxazol, broad spectrum betalactamics and quinolones. As presented in the case of a 55 year old patient with renal transplantation history admitted with a soft tissue infection and diagnosed with a catheter associated bacteremia by C. pauculus, during hospitalization.